Evaluation of hemoglobinopathy carrier rates in Bilecik hemoglobinopathy diagnosis centre
نویسندگان
چکیده
منابع مشابه
Hemoglobinopathy or Analytical Interference?
1 Bégin Military Teaching Hospital, Department of Biology, 94 163 Saint Mandé, France. * Address correspondence to this author at: BéginMilitary TeachingHospital, Department of Biology, 69 avenue de Paris, 94 163 Saint Mandé, France. Fax +33-1-43-98-47-12; e-mail [email protected]. Received March 17, 2015; accepted April 16, 2015. DOI: 10.1373/clinchem.2015.241091 © 2015 American Associ...
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In humans, two pairs of unlike globin chains combine with four heme groups to form hemoglobin (Hb), a protein that is carried by red cells and picks up oxygen in the lungs and delivers it to the peripheral tissues. One of the globin chain pairs in hemoglobin is always alpha (with the exception of the very first weeks of embryogenesis), while the second pair is ―nonalpha.‖ That is, it can be mad...
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Hemoglobinopathies are a group of inherited hemoglobin disorders. Initially described in the subtropical regions, they are now spread all around the world because of migration. Their high frequency and clinical severity make them a major public health problem mostly in Africa due to the limited resources reserved for the management and prevention of these diseases. Despite considerable advances...
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OBJECTIVE To find a hematological parameter and the cut-off level for identification of nonsickling hemoglobinopathies in pregnant women. MATERIALS AND METHODS Venous blood samples of 849 women with singleton pregnancies were collected at the first visit. All women who met inclusion criteria were examined for nonsickling hemoglobinopathy. On the basis of the sensitivity and the specificity of...
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ژورنال
عنوان ژورنال: Journal of Clinical and Analytical Medicine
سال: 2019
ISSN: 1309-0720,1309-2014
DOI: 10.4328/jcam.5862